HomeProceduresBreast Cancer Surgery (Mastectomy)

Breast Cancer Surgery (Mastectomy)

Surgical removal of one or both breasts to treat breast cancer, with options for skin- or nipple-sparing techniques and immediate or delayed reconstruction.

Surgical Breast and axillary lymph nodes Avg. stay 10 days 0 clinics

Overview

Mastectomy is the surgical removal of the entire breast and is used to treat breast cancer that cannot be managed by breast-conserving surgery, recurrent disease after lumpectomy and radiotherapy, certain genetic high-risk cases (BRCA1/2 risk-reducing mastectomy), and selected cases of ductal carcinoma in situ. Bilateral (double) mastectomy is offered when both breasts are affected or when a high-risk-reducing strategy is chosen. Modern mastectomy can be performed as a simple (total) mastectomy with removal of the breast and overlying skin and nipple, or as a skin-sparing or nipple-sparing mastectomy when immediate reconstruction is planned. Sentinel lymph node biopsy or axillary clearance is usually performed at the same time to stage the axilla. Reconstruction can be performed immediately with an implant, expander, or autologous tissue flap (DIEP, latissimus dorsi), or delayed until adjuvant therapy is complete. NHS guidance describes a recovery time of about three weeks to return to most usual activities and around six weeks for full wound healing. International patients typically remain in-country for 10-14 days for drain removal, wound check and oncology multidisciplinary planning of adjuvant therapy (chemotherapy, radiotherapy, endocrine and targeted therapy). Survivorship care includes lymphoedema surveillance, scar management and psychological support. Sources: NHS, NICE breast cancer guidelines, AAFP.

Hospital & stay

2–3 nights
Hospital stay
10 days
Total stay abroad
Surgical
Procedure type

Procedure details

How it's performed

Under general anaesthesia, the surgeon makes a horizontal elliptical incision across the chest from under the arm towards the breastbone (or a smaller incision for skin-/nipple-sparing approaches). The breast tissue is dissected off the underlying pectoralis major fascia and removed en bloc. A sentinel node biopsy or axillary clearance is performed through a separate axillary incision or the same incision. One or more closed-suction drains are placed before the skin is closed. If immediate reconstruction is planned, the plastic surgical team then proceeds with implant or autologous flap insertion.

Preparation
  1. 1Confirm diagnosis with image-guided core biopsy, breast MRI/staging imaging and multidisciplinary team plan.
  2. 2Pre-operative bloods, ECG, anaesthetic review and discussion of reconstruction options.
  3. 3Stop smoking 6-8 weeks before to optimise flap and wound healing.
  4. 4Mark sentinel node with radioisotope or dye on the day of surgery.
  5. 5Arrange post-discharge support, drain management training and post-mastectomy bra/prosthesis fitting.
Recovery
  1. 1Day 0-1: Hospital stay overnight with closed-suction drains; intravenous analgesia and shoulder exercises begin.
  2. 2Days 1-7: Discharge with drains; daily wound and drain monitoring at home or in clinic.
  3. 3Days 7-14: Drain removal once output is low; wound check by breast care nurse.
  4. 4Weeks 2-3: Return to most usual activities; continue gentle shoulder rehabilitation.
  5. 5Weeks 4-6: Full wound healing; oncology team reviews need for adjuvant chemotherapy, radiotherapy or endocrine therapy.
  6. 6Months 3-12: Surveillance imaging, lymphoedema monitoring and any planned delayed reconstruction.

Related procedures

Related procedures

Evidence Guiding Breast Cancer Surgery and Mastectomy

12 peer-reviewed sources

Surgical management of breast cancer has evolved through decades of randomized trials and large cohort studies toward more individualized, often less extensive, operations. The references below include long-term randomized data, systematic reviews and meta-analyses comparing mastectomy with breast-conserving surgery, and high-quality evidence on de-escalation of axillary surgery and sentinel lymph node biopsy. They show that, for appropriately selected patients, breast conservation can offer survival comparable to mastectomy, and that omitting extensive axillary dissection is safe in many node-negative and selected node-positive settings. Because the right operation depends on tumor biology, stage, genetics, and personal preference, these sources are intended to support shared decision-making with a multidisciplinary breast cancer team rather than to recommend any single approach.

  1. Survival after breast-conserving surgery and radiotherapy versus mastectomy: propensity score analyses within a randomized anaesthesiology trial.
    Wadsten C, et al. · British Journal of Surgery · 2026
    Randomized controlled trialPMID 41954954DOI
  2. Twenty-year results of the randomized EORTC trial 22922/10925 evaluating internal mammary chain and medial supraclavicular lymph node irradiation in stage I-III breast cancer.
    Kaidar-Person O, et al. · CA: A Cancer Journal for Clinicians · 2026
    Randomized controlled trialPMID 42141924DOI
  3. Surgical Outcomes After Neoadjuvant Pembrolizumab Plus Chemotherapy for Triple-Negative Breast Cancer: Results from the Randomized, Placebo-Controlled Phase 3 KEYNOTE-522 Study.
    Kuemmel S, et al. · Annals of Surgical Oncology · 2026
    Randomized controlled trialPMID 41739398DOI
  4. Oncologic safety of breast-conserving surgery in node-positive breast cancer: a systematic review and meta-analysis.
    Sun J, Lin S. · Gland Surgery · 2026
    Meta-analysisPMID 41668907DOI
  5. Omission of axillary surgery in early breast cancer with negative lymph nodes: a systematic review and meta-analysis of randomized clinical trials.
    Castelo BB, et al. · Breast Cancer Research and Treatment · 2026
    Meta-analysisPMID 41848913DOI

Compiled from peer-reviewed medical literature indexed on PubMed. This overview is for general education and is not medical advice. · Last updated 2026-06-15