Kidney Transplant
A donor kidney is placed in the iliac fossa with vascular and ureteric anastomoses to treat end-stage kidney disease; the native kidneys are usually left in place.
Overview
Hospital & stay
Procedure details
How it's performed
Under general anaesthesia, the surgeon makes an oblique lower-abdominal (iliac fossa) incision and dissects extraperitoneally to expose the external iliac artery and vein. The donor kidney is brought to the field on ice. The renal vein is anastomosed end-to-side to the external iliac vein, then the renal artery to the external iliac artery; clamps are released and the kidney reperfused. The donor ureter is implanted into the bladder over a double-J stent. The wound is closed in layers and a closed-suction drain may be placed.
Preparation
- 1Comprehensive transplant work-up: tissue typing, virology, cardiac and pulmonary fitness, dental review.
- 2Listing on the national transplant registry; or directed/altruistic living-donor work-up.
- 3Optimise dialysis and fluid balance; treat any infection or peripheral vascular disease.
- 4Vaccinations (hepatitis B, pneumococcus, influenza, varicella) before transplantation.
- 5Cross-match and pre-operative bloods; patient education on lifelong immunosuppression and self-monitoring.
Recovery
- 1Day 0-1: High-dependency monitoring; urine output and creatinine tracked closely.
- 2Days 1-7: Ward-based recovery with daily ultrasound if indicated; immunosuppression initiated and adjusted.
- 3Days 5-10: Discharge once graft function is stable, drain removed and patient self-caring.
- 4Weeks 2-6: Twice-weekly outpatient bloods initially, decreasing as graft function stabilises.
- 5Weeks 6-12: Double-J stent removed at cystoscopy; gradual return to work.
- 6Lifelong: Annual review, cancer and infection surveillance, lifelong immunosuppression.
Related procedures
Related procedures
What the research says about kidney transplantation
14 peer-reviewed sourcesKidney transplantation is widely regarded as the treatment of choice for many people with kidney failure, offering survival and quality-of-life advantages over long-term dialysis in suitable candidates. Evidence from registry cohorts, systematic reviews, and clinical practice guidelines informs donor selection, immunosuppression, and the prevention of complications such as rejection, infection, and post-transplant diabetes. Graft and patient survival have improved over time, though outcomes depend on donor type, recipient health, and lifelong adherence to medication and follow-up. Ongoing research addresses older recipients, ABO-incompatible transplantation, organ preservation, and cardiovascular and metabolic risk after surgery. The references below are drawn from peer-reviewed meta-analyses, Cochrane reviews, registry analyses, and guideline-level sources.
- The Role of Rituximab in ABO-Compatible Renal Transplantation: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Trials.
- Kidney transplantation in adult candidates with obesity: Guidelines by the Association Française d'Urologie and Société Francophone de Transplantation.
- Evaluating Infections in Solid Organ Donors Before Transplantation: A Systematic Review of Clinical Practice Guidelines.
- Kidney transplant outcomes in patients aged ≥ 70 years: a systematic review and meta-analysis of multicenter or registry-based studies with future directions and a multicenter study proposal.
- Cardiovascular and Renal Outcomes Among Kidney Transplant Recipients With Metabolic Syndrome: A Systematic Review and Meta-Analysis.
Compiled from peer-reviewed medical literature indexed on PubMed. This overview is for general education and is not medical advice. · Last updated 2026-06-15